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1.
Frontiers in psychiatry ; 13, 2022.
Article in English | EuropePMC | ID: covidwho-1981268

ABSTRACT

Objective To conduct a large cross-sectional survey of the mental health of college students during the recovery period of the COVID-19 epidemic. Methods Symptom Checklist 90 (SCL-90) and COVID-19 questionnaire were used to investigate the overall mental health level and cognition of epidemic situation of college students in seven colleges and universities in Shaanxi Province. Results (1) In the recovery period of COVID-19 epidemic, college students still had psychological and somatic symptoms such as obsessive-compulsive disorder, interpersonal sensitivity, anxiety, hostility, and poor appetite or insomnia;(2) female college students, science and engineering college students, freshmen and senior graduates, and some ethnic minority college students were all groups with psychological symptoms;(3) the psychological status of college students was related to their perception of COVID-19 epidemic, and the more knowledge about epidemic prevention and control, the more confident they were in overcoming the epidemic, and the milder the psychological symptoms. Conclusion College students still have some mental health problems in the recovery period of COVID-19 epidemic, which should be paid attention to by education authorities and colleges and universities.

2.
medrxiv; 2022.
Preprint in English | medRxiv | ID: ppzbmed-10.1101.2022.04.01.22273291

ABSTRACT

BackgroundAs a new infectious disease affecting the world, COVID-19 has caused a huge impact on countries around the world. At present, its specific pathophysiological mechanism has not been fully clarified. We found in the analysis of the arterial blood gas data of critically ill patients that the incidence of metabolic alkalosis in such patients is high. MethodWe retrospectively analyzed the arterial blood gas analysis results of a total of 16 critically ill patients in the intensive ICU area of Xiaogan Central Hospital and 42 severe patients in the intensive isolation ward, and analyzed metabolic acidosis and respiratory acidosis. Metabolic alkalosis and respiratory alkalosis, and the relationship between metabolic alkalosis and death. ResultAmong the 16 critically ill patients, the incidence of metabolic alkalosis was 100%, while the incidence of metabolic alkalosis in severe patients was 50%; the mortality rate in critically ill patients was 81.3%, and 21.4% in severe patients; The mortality of all patients with metabolic alkalosis is 95.5%,and 4.5% in without metabolic alkalosis. ConclusionThe incidence of metabolic alkalosis in critically ill COVID-19 patients is high, and it is associated with high mortality.


Subject(s)
Alkalosis , Alkalosis, Respiratory , Critical Illness , Acidosis , Death , COVID-19 , Acidosis, Respiratory
3.
researchsquare; 2020.
Preprint in English | PREPRINT-RESEARCHSQUARE | ID: ppzbmed-10.21203.rs.3.rs-132628.v1

ABSTRACT

BackgroundThe lung CT of COVID-19 has characteristic changes, showing scattered ground-glass changes extrapulmonary zone. However, we observe a case of early infection of COVID-19 in a patient who did not show classic CT changes, but shows characteristic pulmonary fibrosis.Case presentationWe reported a patient who was infected in the early stage of the COVID epidemic without any treatment. The extrapulmonary zone showed symmetrical and diffuse fibrotic changes.Conclusionsthe lungs of COVID-19 may not show scattered ground-glass changes, but show symmetrical, diffuse pulmonary fibrosis in extrapulmonary, suggests that there may be other mechanisms other than infection involved in the changes in the lungs.


Subject(s)
COVID-19 , Pulmonary Fibrosis , Infections
4.
J Clin Virol ; 127: 104359, 2020 06.
Article in English | MEDLINE | ID: covidwho-75271

ABSTRACT

BACKGROUND: COVID-19, the latest outbreak of infectious disease, has caused huge medical challenges to China and the entire globe. No unified diagnostic standard has been formulated. The initial diagnosis remains based on the positive of nucleic acid tests. However, early nucleic acid tests were identified to be negative in some patients, whereas the patients exhibited characteristic CT changes of lung, and positive test results appeared after repeated nucleic acid tests, having caused the failure to diagnose these patients early. The study aimed to delve into the relationships between initial nucleic acid testing and early lung CT changes in patients with COVID-19. METHOD: In accordance with the latest COVID-19 diagnostic criteria, 69 patients diagnosed with COVID-19 treated in the infected V ward of Xiaogan Central Hospital from 2020/1/25 to 2020/2/6 were retrospectively analyzed. The consistency between the first COVID-19 nucleic acid test positive and lung CT changes was studied. In addition, the sensitivity and specificity of CT and initial nucleic acid were studied. RESULT: The Kappa coefficient of initial nucleic acid positive changes and lung CT changes was -1.52. With a positive nucleic acid test as the gold standard, the sensitivity of lung CT was 12.00 %, 95 % CI: 4.6-24.3; with the changes of CT as the gold standard, the sensitivity of nucleic acid positive was 30.16 %, 95 % CI: 19.2-43.0. CONCLUSION: The consistency between the initial positive nucleic acid test and the CT changes in the lungs is poor; low sensitivity was achieved for initial nucleic acid detection and CT changes.


Subject(s)
Coronavirus Infections/diagnosis , DNA, Viral/isolation & purification , Lung/diagnostic imaging , Pneumonia, Viral/diagnosis , Adult , Aged , Aged, 80 and over , Betacoronavirus/isolation & purification , COVID-19 , COVID-19 Testing , Clinical Laboratory Techniques , Coronavirus Infections/diagnostic imaging , Female , Humans , Lung/virology , Male , Middle Aged , Molecular Diagnostic Techniques , Pandemics , Pharynx/virology , Pneumonia, Viral/diagnostic imaging , Retrospective Studies , SARS-CoV-2 , Sensitivity and Specificity , Tomography, X-Ray Computed , Young Adult
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